Q&A 452: Does NR or NAD Cause Cancer, Latest On THC, & More
January 5, 2023
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News Flashes – Follow Ben on Twitter for more…
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- Nicotinamide Riboside (NR), also known as niacin, is the building block of NAD.
- NAD is a critical molecule that allows your body to generate energy from food.
- Preferred NAD supplements include
- NR is a cellular protectant.
- Azido NR includes an added nitrogen, which means:
- It can’t be turned into NAD
- It can be tracked in the body
- Triple-negative breast cancer cells took up 4 times the amount of NR as the other cancer cells.
- Negative for estrogen receptor
- Negative for progesterone receptor
- Negative for the growth factor HER2
- Brain metastasis was found in mice that were injected with cancer cells and given NR.
- The dose given was equivalent to an average dose that people supplement: 25-30 mg.
- Should you stop taking NR?
- The book The China Study claims that protein causes cancer. However, cancer was already present when they did the study.
- When cancer isn’t present, does NR give you cancer?
- Similar to The China Study, the NR study assumes cancer is present
- If you have cancer, avoid taking NR, NAD, or NMN. Otherwise, it’s fine to supplement with NR.
- Wow: THC exposure alters brain maximal oxidative capacity. It impairs mainly the complexes I, II, and III of the mitochondrial respiratory chain and mitochondrial coupling. THC also increases brain ROS production and mitochondrial free radical leak: Tetrahydrocannabinol Induces Brain Mitochondrial Respiratory Chain Dysfunction and Increases Oxidative Stress: A Potential Mechanism Involved in Cannabis-Related Stroke…14:06
- High-THC cannabis appears to be a risk factor for ischemic stroke in young adults.
- When the inner mitochondrial membrane produces energy, it releases free radicals. This is normal.
- Study looks at whether or not THC increases the reactive oxygen species production in the mitochondria in the brain.
- They found a significant increase in free radical leakage in the brains of mice.
- This means — theoretically, and especially if you are a mouse — that your brain goes into free radical-overproduction-hyper-drive when exposed to high amounts of THC cannabis.
- Consuming foods high in antioxidants can help mitigate the overproduction of free radicals when using THC.
- Can CBD (with or without THC) improve sleep? Here’s the answer: Use of Cannabidiol in the Management of Insomnia: A Systematic Review…19:42
- CBD alone, or CBD in a 1:1 ratio with THC, can be beneficial for alleviating the symptoms of insomnia.
- The study fails to mention that THC consumption can cause a decrease in deep sleep, as well as dreaming and memory consolidation during sleep.
- Ben’s Yoga Nidra practice for insomnia which he first learned about from Dr. Andrew Huberman.
- Element Health CBD is preferred CBD supplement (use code BEN15 to save 15%).
- CBD alone, or CBD in a 1:1 ratio with THC, can be beneficial for alleviating the symptoms of insomnia.
Resources mentioned:
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Click here for the full written transcript of this podcast episode.
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